CEO · Founder · Inventor

Wesley Wierson

CEO, LEAH Labs & VelociTx  ·  GeneWeld Inventor

Wesley Wierson is a biotech founder and genome editing scientist. He invented GeneWeld — a virus-free CRISPR precision knock-in platform — and co-founded LEAH Labs and VelociTx to translate gene-edited cell therapies into the clinic. His published work spans CRISPR tool development, zebrafish genetics, and AI-assisted biomedical science.

GeneWeld Inventor CRISPR Genome Editing CAR-T Cell Therapy Zebrafish Genetics Biotech Founder

Companies & platforms

LEAH Labs
Co-Founder & CEO · Gene-edited CAR-T therapy for veterinary and human oncology
VelociTx
Co-Founder & CEO · T cell immunotherapy for solid tumors
GeneWeld
Inventor · Virus-free CRISPR precision knock-in platform

Selected works

"VaaS is a Multi-Layer Hallucination Reduction Pipeline for AI-Assisted Science: Production Validation and Prospective Benchmarking"
Sabharwal A, Patel MS, Carrano A, Rotman M, Wierson W, Ekker SC  ·  medRxiv · 2026
medRxiv
"Rbbp4 loss disrupts neural progenitor cell cycle regulation independent of Rb and leads to neurodegeneration"
Schultz-Rogers LE, Thayer ML, Kambakam S, Wierson WA et al.  ·  Developmental Dynamics · 2022
PMID 35266256
"GeneWeld: Efficient Targeted Integration Directed by Short Homology in Zebrafish"
Welker JM, Wierson WA, Almeida MP, Mann CM et al.  ·  Bio-protocol · 2021
PMID 34395736
"Efficient targeted integration directed by short homology in zebrafish and mammalian cells"
Wierson WA, Welker JM, Almeida MP, Mann CM et al.  ·  eLife · 2020
PMID 32412410
"Expanding the CRISPR Toolbox with ErCas12a in Zebrafish and Human Cells"
Wierson WA, Simone BW, WareJoncas Z, Mann C et al.  ·  The CRISPR Journal · 2019
PMID 31742435
"The Gene Sculpt Suite: a set of tools for genome editing"
Mann CM, Martínez-Gálvez G, Welker JM, Wierson WA et al.  ·  Nucleic Acids Research · 2019
PMID 31127311
"CAR T Cell Immunotherapy in Human and Veterinary Oncology: Changing the Odds Against Hematological Malignancies"
Mochel JP, Ekker SC, Johannes CM, Jergens AE, Wierson W et al.  ·  The AAPS Journal · 2019
PMID 30963322
"Epigenetic regulators Rbbp4 and Hdac1 are overexpressed in a zebrafish model of RB1 embryonal brain tumor"
Schultz LE, Haltom JA, Almeida MP, Wierson WA et al.  ·  Disease Models & Mechanisms · 2018
PMID 29914980
"GoldyTALEN Vectors with Improved Efficiency for Golden Gate TALEN Assembly"
Welker JM, Wierson WA, Wang Y, Poshusta TL et al.  ·  Human Gene Therapy · 2016
PMID 27094430

View full list on PubMed →